Antisense oligonucleotides delivered to the amniotic cavity in utero modulate gene expression in the postnatal mouse

Congenital diseases account for a large portion of pediatric illness. Prenatal screening and diagnosis permit early detection of many genetic diseases. Fetal therapeutic strategies to manage disease processes in utero represent a powerful new approach for clinical care. A safe and effective fetal ph...

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Detalles Bibliográficos
Autores principales: Depreux, Frederic F., Wang, Lingyan, Jiang, Han, Jodelka, Francine M., Rosencrans, Robert F., Rigo, Frank, Lentz, Jennifer J., Brigande, John V., Hastings, Michelle L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2016
Materias:
NAR Breakthrough Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5175366/
https://www.ncbi.nlm.nih.gov/pubmed/27683224
http://dx.doi.org/10.1093/nar/gkw867

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5175366/
https://www.ncbi.nlm.nih.gov/pubmed/27683224
http://dx.doi.org/10.1093/nar/gkw867

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