Function-driven discovery of disease genes in zebrafish using an integrated genomics big data resource

Whole exome sequencing (WES) accelerates disease gene discovery using rare genetic variants, but further statistical and functional evidence is required to avoid false-discovery. To complement variant-driven disease gene discovery, here we present function-driven disease gene discovery in zebrafish...

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Detalles Bibliográficos
Autores principales: Shim, Hongseok, Kim, Ji Hyun, Kim, Chan Yeong, Hwang, Sohyun, Kim, Hyojin, Yang, Sunmo, Lee, Ji Eun, Lee, Insuk
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2016
Materias:
Data Resources and Analyses
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5175370/
https://www.ncbi.nlm.nih.gov/pubmed/27903883
http://dx.doi.org/10.1093/nar/gkw897

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5175370/
https://www.ncbi.nlm.nih.gov/pubmed/27903883
http://dx.doi.org/10.1093/nar/gkw897

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