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A high complex karyotype involving eleven chromosomes including three novel chromosomal aberrations and monoallelic loss of TP53 in case of follicular lymphoma transformed into B-cell lymphoblastic leukemia

BACKGROUND: Follicular lymphoma (FL) is one of the most common B-cell non-Hodgkin’s lymphoma (NHL). A subset of FL cases transform into more aggressive malignancies, most often to diffuse large B-cell lymphoma (DLBCL); in addition, lymphoblastic lymphoma and acute lymphoblastic leukemia (ALL) have a...

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Detalles Bibliográficos
Autores principales: Wafa, Abdulsamad, Moassass, Faten, Liehr, Thomas, Bhatt, Samarth, Aljapawe, Abdulmunim, Al Achkar, Walid
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5175377/
https://www.ncbi.nlm.nih.gov/pubmed/28031746
http://dx.doi.org/10.1186/s13039-016-0300-6

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