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Optimal Acquisition Number for Hepatic Shear Wave Velocity Measurements in Children

OBJECTIVE: To investigate the minimum optimal acquisition number of hepatic shear wave velocities (SWVs) on ultrasound elastography in children. MATERIALS AND METHODS: We prospectively performed hepatic supersonic shear wave elastography in children of four groups (group A-C, healthy children, group...

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Autores principales: Shin, Hyun Joo, Kim, Myung-Joon, Kim, Ha Yan, Roh, Yun Ho, Lee, Mi-Jung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5176183/
https://www.ncbi.nlm.nih.gov/pubmed/28002480
http://dx.doi.org/10.1371/journal.pone.0168758
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author Shin, Hyun Joo
Kim, Myung-Joon
Kim, Ha Yan
Roh, Yun Ho
Lee, Mi-Jung
author_facet Shin, Hyun Joo
Kim, Myung-Joon
Kim, Ha Yan
Roh, Yun Ho
Lee, Mi-Jung
author_sort Shin, Hyun Joo
collection PubMed
description OBJECTIVE: To investigate the minimum optimal acquisition number of hepatic shear wave velocities (SWVs) on ultrasound elastography in children. MATERIALS AND METHODS: We prospectively performed hepatic supersonic shear wave elastography in children of four groups (group A-C, healthy children, group A with 0–5 years old; group B with 6–10 years old; group C with 11–18 years old; and group D, children with previous Kasai operation) with free breathing (FB) and breath holding (BH) status, if possible. SWVs were measured fifteen times for each child at a 4 cm depth for the right lobe using a 1–6 MHz convex transducer. Mean SWVs from three, five, and seven acquisitions were compared to the mean SWV from fifteen measurements, using an intraclass correlation coefficient (ICC) analyzed with the 1,000 times bootstrap method. RESULTS: Total eighty-eight children were included (25 children in group A, 30 children in group B, 21 children in group C, and 12 children in group D). The mean SWVs from fifteen measurements in FB status were 5.5 ± 1.3 kPa for groups A-C together and 8.0 ± 2.2 kPa for group D. For all groups together, mean SWVs from the three (ICC 0.944 and 0.937), five (ICC 0.958 and 0.938) and seven (ICC 0.969 and 0.941) acquisitions demonstrated almost perfect agreement with the reference of fifteen acquisitions in both FB and BH status, respectively. A subgroup analysis showed three measurements were in almost perfect agreement during FB for groups B-D and strong agreement (ICC 0.675) for group A. CONCLUSION: Three acquisitions can be enough for hepatic SWVs in children more than 6 years old regardless of breathing status or hepatic pathology. More acquisitions are recommended for children under the age of 5 years during FB.
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spelling pubmed-51761832017-01-04 Optimal Acquisition Number for Hepatic Shear Wave Velocity Measurements in Children Shin, Hyun Joo Kim, Myung-Joon Kim, Ha Yan Roh, Yun Ho Lee, Mi-Jung PLoS One Research Article OBJECTIVE: To investigate the minimum optimal acquisition number of hepatic shear wave velocities (SWVs) on ultrasound elastography in children. MATERIALS AND METHODS: We prospectively performed hepatic supersonic shear wave elastography in children of four groups (group A-C, healthy children, group A with 0–5 years old; group B with 6–10 years old; group C with 11–18 years old; and group D, children with previous Kasai operation) with free breathing (FB) and breath holding (BH) status, if possible. SWVs were measured fifteen times for each child at a 4 cm depth for the right lobe using a 1–6 MHz convex transducer. Mean SWVs from three, five, and seven acquisitions were compared to the mean SWV from fifteen measurements, using an intraclass correlation coefficient (ICC) analyzed with the 1,000 times bootstrap method. RESULTS: Total eighty-eight children were included (25 children in group A, 30 children in group B, 21 children in group C, and 12 children in group D). The mean SWVs from fifteen measurements in FB status were 5.5 ± 1.3 kPa for groups A-C together and 8.0 ± 2.2 kPa for group D. For all groups together, mean SWVs from the three (ICC 0.944 and 0.937), five (ICC 0.958 and 0.938) and seven (ICC 0.969 and 0.941) acquisitions demonstrated almost perfect agreement with the reference of fifteen acquisitions in both FB and BH status, respectively. A subgroup analysis showed three measurements were in almost perfect agreement during FB for groups B-D and strong agreement (ICC 0.675) for group A. CONCLUSION: Three acquisitions can be enough for hepatic SWVs in children more than 6 years old regardless of breathing status or hepatic pathology. More acquisitions are recommended for children under the age of 5 years during FB. Public Library of Science 2016-12-21 /pmc/articles/PMC5176183/ /pubmed/28002480 http://dx.doi.org/10.1371/journal.pone.0168758 Text en © 2016 Shin et al http://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/) , which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Research Article
Shin, Hyun Joo
Kim, Myung-Joon
Kim, Ha Yan
Roh, Yun Ho
Lee, Mi-Jung
Optimal Acquisition Number for Hepatic Shear Wave Velocity Measurements in Children
title Optimal Acquisition Number for Hepatic Shear Wave Velocity Measurements in Children
title_full Optimal Acquisition Number for Hepatic Shear Wave Velocity Measurements in Children
title_fullStr Optimal Acquisition Number for Hepatic Shear Wave Velocity Measurements in Children
title_full_unstemmed Optimal Acquisition Number for Hepatic Shear Wave Velocity Measurements in Children
title_short Optimal Acquisition Number for Hepatic Shear Wave Velocity Measurements in Children
title_sort optimal acquisition number for hepatic shear wave velocity measurements in children
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5176183/
https://www.ncbi.nlm.nih.gov/pubmed/28002480
http://dx.doi.org/10.1371/journal.pone.0168758
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