Sequence Analysis of Toxin Gene–Bearing Corynebacterium diphtheriae Strains, Australia

By conducting a molecular characterization of Corynebacterium diphtheriae strains in Australia, we identified novel sequences, nonfunctional toxin genes, and 5 recent cases of toxigenic cutaneous diphtheria. These findings highlight the importance of extrapharyngeal infections for toxin gene–bearing...

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Detalles Bibliográficos
Autores principales: Doyle, Christine J., Mazins, Adam, Graham, Rikki M.A., Fang, Ning-Xia, Smith, Helen V., Jennison, Amy V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Centers for Disease Control and Prevention 2017
Materias:
Dispatch
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5176206/
https://www.ncbi.nlm.nih.gov/pubmed/27983494
http://dx.doi.org/10.3201/eid2301.160584
Descripción
Sumario:By conducting a molecular characterization of Corynebacterium diphtheriae strains in Australia, we identified novel sequences, nonfunctional toxin genes, and 5 recent cases of toxigenic cutaneous diphtheria. These findings highlight the importance of extrapharyngeal infections for toxin gene–bearing (functional or not) and non–toxin gene–bearing C. diphtheriae strains. Continued surveillance is recommended.

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