Unique Molecular Patterns Uncovered in Kawasaki Disease Patients with Elevated Serum Gamma Glutamyl Transferase Levels: Implications for Intravenous Immunoglobulin Responsiveness

BACKGROUND: Resistance to intravenous immunoglobulin (IVIG) occurs in 10–20% of patients with Kawasaki disease (KD). The risk of resistance is about two-fold higher in patients with elevated gamma glutamyl transferase (GGT) levels. We sought to understand the biological mechanisms underlying IVIG re...

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Detalles Bibliográficos
Autores principales: Wang, Yue, Li, Zhen, Hu, Guang, Hao, Shiying, Deng, Xiaohong, Huang, Min, Ren, Miao, Jiang, Xiyuan, Kanegaye, John T., Ha, Kee-Soo, Lee, JungHwa, Li, Xiaofeng, Jiang, Xuejun, Yu, Yunxian, Tremoulet, Adriana H., Burns, Jane C., Whitin, John C., Shin, Andrew Y., Sylvester, Karl G., McElhinney, Doff B., Cohen, Harvey J., Ling, Xuefeng B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5176264/
https://www.ncbi.nlm.nih.gov/pubmed/28002448
http://dx.doi.org/10.1371/journal.pone.0167434

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