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Dose-Finding Study of Omeprazole on Gastric pH in Neonates with Gastro-Esophageal Acid Reflux Using a Bayesian Sequential Approach

OBJECTIVE: Proton pump inhibitors are frequently administered on clinical symptoms in neonates but benefit remains controversial. Clinical trials validating omeprazole dosage in neonates are limited. The objective of this trial was to determine the minimum effective dose (MED) of omeprazole to treat...

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Detalles Bibliográficos
Autores principales:	Kaguelidou, Florentia, Alberti, Corinne, Biran, Valerie, Bourdon, Olivier, Farnoux, Caroline, Zohar, Sarah, Jacqz-Aigrain, Evelyne
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2016
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5176365/ https://www.ncbi.nlm.nih.gov/pubmed/28002471 http://dx.doi.org/10.1371/journal.pone.0166207

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