Zika Virus Infection and Guillain–Barré Syndrome in Three Patients from Suriname

We present three patients from Suriname who were diagnosed with Guillain–Barré syndrome (GBS) during the Zika virus (ZIKV) outbreak in this country. One patient had a positive ZIKV urine real-time RT-PCR (qRT-PCR) result. The other two patients had a negative ZIKV urine qRT-PCR but a positive virus...

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Detalles Bibliográficos
Autores principales: Langerak, Thomas, Yang, Harvey, Baptista, Mark, Doornekamp, Laura, Kerkman, Tessa, Codrington, John, Roosblad, Jimmy, Vreden, Stephen G. S., De Bruin, Erwin, Mögling, Ramona, Jacobs, Bart C., Pas, Suzan D., GeurtsvanKessel, Corine H., Reusken, Chantal B. E. M., Koopmans, Marion P., Van Gorp, Eric C. M., Alberga, Henk
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2016
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5177614/
https://www.ncbi.nlm.nih.gov/pubmed/28066317
http://dx.doi.org/10.3389/fneur.2016.00233
Descripción
Sumario:We present three patients from Suriname who were diagnosed with Guillain–Barré syndrome (GBS) during the Zika virus (ZIKV) outbreak in this country. One patient had a positive ZIKV urine real-time RT-PCR (qRT-PCR) result. The other two patients had a negative ZIKV urine qRT-PCR but a positive virus neutralization test and presence of IgG antibodies against ZIKV in the serum. Considering the evidence of a past ZIKV infection and absence of evidence for recent infections with the most common preceding infections of GBS, it is very likely that these GBS cases were triggered by ZIKV.

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