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Complement Protein C1q Interacts with DC-SIGN via Its Globular Domain and Thus May Interfere with HIV-1 Transmission
Dendritic cells (DCs) are the most potent antigen-presenting cells capable of priming naïve T-cells. Its C-type lectin receptor, DC-SIGN, regulates a wide range of immune functions. Along with its role in HIV-1 pathogenesis through complement opsonization of the virus, DC-SIGN has recently emerged a...
Autores principales: | Pednekar, Lina, Pandit, Hrishikesh, Paudyal, Basudev, Kaur, Anuvinder, Al-Mozaini, Maha Ahmed, Kouser, Lubna, Ghebrehiwet, Berhane, Mitchell, Daniel A., Madan, Taruna, Kishore, Uday |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5177617/ https://www.ncbi.nlm.nih.gov/pubmed/28066413 http://dx.doi.org/10.3389/fimmu.2016.00600 |
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