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Immunometabolic Pathways in BCG-Induced Trained Immunity

The protective effects of the tuberculosis vaccine Bacillus Calmette-Guerin (BCG) on unrelated infections are thought to be mediated by long-term metabolic changes and chromatin remodeling through histone modifications in innate immune cells such as monocytes, a process termed trained immunity. Here...

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Detalles Bibliográficos
Autores principales:	Arts, Rob J.W., Carvalho, Agostinho, La Rocca, Claudia, Palma, Carla, Rodrigues, Fernando, Silvestre, Ricardo, Kleinnijenhuis, Johanneke, Lachmandas, Ekta, Gonçalves, Luís G., Belinha, Ana, Cunha, Cristina, Oosting, Marije, Joosten, Leo A.B., Matarese, Giuseppe, van Crevel, Reinout, Netea, Mihai G.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Cell Press 2016
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5177620/ https://www.ncbi.nlm.nih.gov/pubmed/27926861 http://dx.doi.org/10.1016/j.celrep.2016.11.011

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