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Vav Proteins Are Key Regulators of Card9 Signaling for Innate Antifungal Immunity
Fungal infections are major causes of morbidity and mortality, especially in immunocompromised individuals. The innate immune system senses fungal pathogens through Syk-coupled C-type lectin receptors (CLRs), which signal through the conserved immune adaptor Card9. Although Card9 is essential for an...
Autores principales: | , , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cell Press
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5177621/ https://www.ncbi.nlm.nih.gov/pubmed/27926862 http://dx.doi.org/10.1016/j.celrep.2016.11.018 |