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Vav Proteins Are Key Regulators of Card9 Signaling for Innate Antifungal Immunity

Fungal infections are major causes of morbidity and mortality, especially in immunocompromised individuals. The innate immune system senses fungal pathogens through Syk-coupled C-type lectin receptors (CLRs), which signal through the conserved immune adaptor Card9. Although Card9 is essential for an...

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Detalles Bibliográficos
Autores principales: Roth, Susanne, Bergmann, Hanna, Jaeger, Martin, Yeroslaviz, Assa, Neumann, Konstantin, Koenig, Paul-Albert, Prazeres da Costa, Clarissa, Vanes, Lesley, Kumar, Vinod, Johnson, Melissa, Menacho-Márquez, Mauricio, Habermann, Bianca, Tybulewicz, Victor L., Netea, Mihai, Bustelo, Xosé R., Ruland, Jürgen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5177621/
https://www.ncbi.nlm.nih.gov/pubmed/27926862
http://dx.doi.org/10.1016/j.celrep.2016.11.018