Multivalent Histone and DNA Engagement by a PHD/BRD/PWWP Triple Reader Cassette Recruits ZMYND8 to K14ac-Rich Chromatin

Elucidation of interactions involving DNA and histone post-translational-modifications (PTMs) is essential for providing insights into complex biological functions. Reader assemblies connected by flexible linkages facilitate avidity and increase affinity; however, little is known about the contribut...

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Detalles Bibliográficos
Autores principales: Savitsky, Pavel, Krojer, Tobias, Fujisawa, Takao, Lambert, Jean-Philippe, Picaud, Sarah, Wang, Chen-Yi, Shanle, Erin K., Krajewski, Krzysztof, Friedrichsen, Hans, Kanapin, Alexander, Goding, Colin, Schapira, Matthieu, Samsonova, Anastasia, Strahl, Brian D., Gingras, Anne-Claude, Filippakopoulos, Panagis
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5177622/
https://www.ncbi.nlm.nih.gov/pubmed/27926874
http://dx.doi.org/10.1016/j.celrep.2016.11.014

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