Selective Estrogen Receptor Modulators: Cannabinoid Receptor Inverse Agonists with Differential CB1 and CB2 Selectivity

Selective estrogen receptor modulators (SERMs) are used to treat estrogen receptor (ER)-positive breast cancer and osteoporosis. Interestingly, tamoxifen and newer classes of SERMs also exhibit cytotoxic effects in cancers devoid of ERs, indicating a non-estrogenic mechanism of action. Indicative of...

Descripción completa

Detalles Bibliográficos
Autores principales: Franks, Lirit N., Ford, Benjamin M., Prather, Paul L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2016
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5177629/
https://www.ncbi.nlm.nih.gov/pubmed/28066250
http://dx.doi.org/10.3389/fphar.2016.00503

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5177629/
https://www.ncbi.nlm.nih.gov/pubmed/28066250
http://dx.doi.org/10.3389/fphar.2016.00503

Ejemplares similares