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Data Analysis Protocol for the Development and Evaluation of Population Pharmacokinetic Models for Incorporation Into the Web-Accessible Population Pharmacokinetic Service - Hemophilia (WAPPS-Hemo)
BACKGROUND: Hemophilia is an inherited bleeding disorder caused by a deficiency in a specific clotting factor. This results in spontaneous bleeding episodes and eventual arthropathy. The mainstay of hemophilia treatment is prophylactic replacement of the missing factor, but an optimal regimen remain...
Autores principales: | McEneny-King, Alanna, Foster, Gary, Iorio, Alfonso, Edginton, Andrea N |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
JMIR Publications
2016
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5177737/ https://www.ncbi.nlm.nih.gov/pubmed/27927609 http://dx.doi.org/10.2196/resprot.6559 |
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