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Jagged 1 is a major Notch ligand along cholangiocarcinoma development in mice and humans

Intrahepatic cholangiocarcinoma (ICC) is a rare yet deadly malignancy with limited treatment options. Activation of the Notch signalling cascade has been implicated in cholangiocarcinogenesis. However, while several studies focused on the Notch receptors required for ICC development, little is known...

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Detalles Bibliográficos
Autores principales: Che, L, Fan, B, Pilo, M G, Xu, Z, Liu, Y, Cigliano, A, Cossu, A, Palmieri, G, Pascale, R M, Porcu, A, Vidili, G, Serra, M, Dombrowski, F, Ribback, S, Calvisi, D F, Chen, X
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5177771/
https://www.ncbi.nlm.nih.gov/pubmed/27918553
http://dx.doi.org/10.1038/oncsis.2016.73