A combined reference panel from the 1000 Genomes and UK10K projects improved rare variant imputation in European and Chinese samples

Imputation using the 1000 Genomes haplotype reference panel has been widely adapted to estimate genotypes in genome wide association studies. To evaluate imputation quality with a relatively larger reference panel and a reference panel composed of different ethnic populations, we conducted imputatio...

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Detalles Bibliográficos
Autores principales: Chou, Wen-Chi, Zheng, Hou-Feng, Cheng, Chia-Ho, Yan, Han, Wang, Li, Han, Fang, Richards, J. Brent, Karasik, David, Kiel, Douglas P., Hsu, Yi-Hsiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5177868/
https://www.ncbi.nlm.nih.gov/pubmed/28004816
http://dx.doi.org/10.1038/srep39313

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5177868/
https://www.ncbi.nlm.nih.gov/pubmed/28004816
http://dx.doi.org/10.1038/srep39313

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