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Acute transcriptional up-regulation specific to osteoblasts/osteoclasts in medaka fish immediately after exposure to microgravity
Bone loss is a serious problem in spaceflight; however, the initial action of microgravity has not been identified. To examine this action, we performed live-imaging of animals during a space mission followed by transcriptome analysis using medaka transgenic lines expressing osteoblast and osteoclas...
Autores principales: | Chatani, Masahiro, Morimoto, Hiroya, Takeyama, Kazuhiro, Mantoku, Akiko, Tanigawa, Naoki, Kubota, Koji, Suzuki, Hiromi, Uchida, Satoko, Tanigaki, Fumiaki, Shirakawa, Masaki, Gusev, Oleg, Sychev, Vladimir, Takano, Yoshiro, Itoh, Takehiko, Kudo, Akira |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5177882/ https://www.ncbi.nlm.nih.gov/pubmed/28004797 http://dx.doi.org/10.1038/srep39545 |
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