Cargando…

NOD2 dependent neutrophil recruitment is required for early protective immune responses against infectious Litomosoides sigmodontis L3 larvae

Nucleotide-binding oligomerization domain-containing protein 2 (NOD2) recognizes muramyl dipeptide (MDP) of bacterial cell walls, triggering NFκB-induced pro-inflammation. As most human pathogenic filariae contain Wolbachia endobacteria that synthesize the MDP-containing cell wall precursor lipid II...

Descripción completa

Detalles Bibliográficos
Autores principales:	Ajendra, Jesuthas, Specht, Sabine, Ziewer, Sebastian, Schiefer, Andrea, Pfarr, Kenneth, Parčina, Marijo, Kufer, Thomas A., Hoerauf, Achim, Hübner, Marc P.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2016
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5177913/ https://www.ncbi.nlm.nih.gov/pubmed/28004792 http://dx.doi.org/10.1038/srep39648

Ejemplares similares

Development of patent Litomosoides sigmodontis infections in semi-susceptible C57BL/6 mice in the absence of adaptive immune responses
por: Layland, Laura E., et al.
Publicado: (2015)

Human filariasis—contributions of the Litomosoides sigmodontis and Acanthocheilonema viteae animal model
por: Risch, Frederic, et al.
Publicado: (2021)

Potential of Nucleic Acid Receptor Ligands to Improve Vaccination Efficacy against the Filarial Nematode Litomosoides sigmodontis
por: Scheunemann, Johanna F., et al.
Publicado: (2023)

Combinations of registered drugs reduce treatment times required to deplete Wolbachia in the Litomosoides sigmodontis mouse model
por: Specht, Sabine, et al.
Publicado: (2018)

Macrofilaricidal efficacy of single and repeated oral and subcutaneous doses of flubendazole in Litomosoides sigmodontis infected jirds
por: Hübner, Marc P., et al.
Publicado: (2019)

ILC2s Control Microfilaremia During Litomosoides sigmodontis Infection in Rag2(-/-) Mice
por: Reichwald, Julia J., et al.
Publicado: (2022)

The efficacy of the benzimidazoles oxfendazole and flubendazole against Litomosoides sigmodontis is dependent on the adaptive and innate immune system
por: Risch, Frederic, et al.
Publicado: (2023)

Lipid profiling of the filarial nematodes Onchocerca volvulus, Onchocerca ochengi and Litomosoides sigmodontis reveals the accumulation of nematode-specific ether phospholipids in the host
por: Wewer, Vera, et al.
Publicado: (2017)

Migratory phase of Litomosoides sigmodontis filarial infective larvae is associated with pathology and transient increase of S100A9 expressing neutrophils in the lung
por: Karadjian, Gregory, et al.
Publicado: (2017)

S100A8/S100A9 deficiency increases neutrophil activation and protective immune responses against invading infective L3 larvae of the filarial nematode Litomosoides sigmodontis
por: Frohberger, Stefan J., et al.
Publicado: (2020)

Immunization with L. sigmodontis Microfilariae Reduces Peripheral Microfilaraemia after Challenge Infection by Inhibition of Filarial Embryogenesis
por: Ziewer, Sebastian, et al.
Publicado: (2012)

Oxfendazole mediates macrofilaricidal efficacy against the filarial nematode Litomosoides sigmodontis in vivo and inhibits Onchocerca spec. motility in vitro
por: Hübner, Marc P., et al.
Publicado: (2020)

In vivo efficacy of the boron-pleuromutilin AN11251 against Wolbachia of the rodent filarial nematode Litomosoides sigmodontis
por: Ehrens, Alexandra, et al.
Publicado: (2020)

Short-course quinazoline drug treatments are effective in the Litomosoides sigmodontis and Brugia pahangi jird models
por: Hübner, Marc P., et al.
Publicado: (2019)

Susceptibility to L. sigmodontis infection is highest in animals lacking IL-4R/IL-5 compared to single knockouts of IL-4R, IL-5 or eosinophils
por: Frohberger, Stefan J., et al.
Publicado: (2019)

Absence of IL-17A in Litomosoides sigmodontis-infected mice influences worm development and drives elevated filarial-specific IFN-γ
por: Ritter, Manuel, et al.
Publicado: (2018)

The Chemokine CXCL12 Is Essential for the Clearance of the Filaria Litomosoides sigmodontis in Resistant Mice
por: Bouchery, Tiffany, et al.
Publicado: (2012)

Limited role of mast cells during infection with the parasitic nematode Litomosoides sigmodontis
por: Linnemann, Lara Christine, et al.
Publicado: (2020)

Comparative analysis of small RNAs released by the filarial nematode Litomosoides sigmodontis in vitro and in vivo
por: Quintana, Juan F., et al.
Publicado: (2019)

Unbalanced Arginine pathway and altered maturation of pleural macrophages in Th2-deficient mice during Litomosoides sigmodontis filarial infection
por: Remion, Estelle, et al.
Publicado: (2022)

Differential tissular distribution of Litomosoides sigmodontis microfilariae between microfilaremic and amicrofilaremic mice following experimental infection
por: Bouchery, T., et al.
Publicado: (2012)

The immune response of inbred laboratory mice to Litomosoides sigmodontis: A route to discovery in myeloid cell biology
por: Finlay, Conor M., et al.
Publicado: (2020)

Co-infection restrains Litomosoides sigmodontis filarial load and plasmodial P. yoelii but not P. chabaudi parasitaemia in mice
por: Karadjian, Gregory, et al.
Publicado: (2014)

TGFβ depletion does neither modulate acute E. coli-induced inflammatory immune responses nor impair the protective effect by chronic filarial infection
por: Buerfent, Benedikt C., et al.
Publicado: (2019)

Adoptive Transfer of Immune Cells Into RAG2IL-2Rγ-Deficient Mice During Litomosoides sigmodontis Infection: A Novel Approach to Investigate Filarial-Specific Immune Responses
por: Wiszniewsky, Anna, et al.
Publicado: (2021)

Concurrent Infection With the Filarial Helminth Litomosoides sigmodontis Attenuates or Worsens Influenza A Virus Pathogenesis in a Stage-Dependent Manner
por: Hardisty, Gareth R., et al.
Publicado: (2022)

Fitness Cost of Litomosoides sigmodontis Filarial Infection in Mite Vectors; Implications of Infected Haematophagous Arthropod Excretory Products in Host-Vector Interactions
por: Nieguitsila, Adélaïde, et al.
Publicado: (2013)

In vivo kinetics of Wolbachia depletion by ABBV-4083 in L. sigmodontis adult worms and microfilariae
por: Hübner, Marc P., et al.
Publicado: (2019)

ST2 Deficiency Does Not Impair Type 2 Immune Responses during Chronic Filarial Infection but Leads to an Increased Microfilaremia Due to an Impaired Splenic Microfilarial Clearance
por: Ajendra, Jesuthas, et al.
Publicado: (2014)

Chronic Filarial Infection Provides Protection against Bacterial Sepsis by Functionally Reprogramming Macrophages
por: Gondorf, Fabian, et al.
Publicado: (2015)

Helminth antigens differentially modulate the activation of CD4(+) and CD8(+) T lymphocytes of convalescent COVID-19 patients in vitro
por: Adjobimey, Tomabu, et al.
Publicado: (2022)

Global Distribution Patterns of Carbapenemase-Encoding Bacteria in a New Light: Clues on a Role for Ethnicity
por: Neidhöfer, Claudio, et al.
Publicado: (2021)

STUDIES ON THE METABOLISM OF THE FILARIAL WORM, LITOMOSOIDES CARINII
por: Bueding, Ernest
Publicado: (1949)

Comparison of IgA, IgG, and Neutralizing Antibody Responses Following Immunization With Moderna, BioNTech, AstraZeneca, Sputnik-V, Johnson and Johnson, and Sinopharm’s COVID-19 Vaccines
por: Adjobimey, Tomabu, et al.
Publicado: (2022)

Identification and ultrastructural characterization of the Wolbachia symbiont in Litomosoides chagasfilhoi
por: Chagas-Moutinho, Vanessa Aparecida, et al.
Publicado: (2015)

ESBL Detection: Comparison of a Commercially Available Chromogenic Test for Third Generation Cephalosporine Resistance and Automated Susceptibility Testing in Enterobactericeae
por: El-Jade, Mohamed Ramadan, et al.
Publicado: (2016)

Correction: ESBL Detection: Comparison of a Commercially Available Chromogenic Test for Third Generation Cephalosporine Resistance and Automated Susceptibility Testing in Enterobactericeae
por: El-Jade, Mohamed Ramadan, et al.
Publicado: (2018)

Quinolone-fused cyclic sulfonamide as a novel benign antifilarial agent
por: Mukherjee, Suprabhat, et al.
Publicado: (2018)

The Annotated Genome of Wolbachia from the Filarial Nematode Brugia malayi: What It Means for Progress in Antifilarial Medicine
por: Pfarr, Kenneth, et al.
Publicado: (2005)

Impact of Rifaximin on the Frequency and Characteristics of Spontaneous Bacterial Peritonitis in Patients with Liver Cirrhosis and Ascites
por: Lutz, Philipp, et al.
Publicado: (2014)

Cannot write session to /tmp/vufind_sessions/sess_3424vgehrdp3tcd2uiork5a9vn