Role of CaMKII and PKA in Early Afterdepolarization of Human Ventricular Myocardium Cell: A Computational Model Study

Early afterdepolarization (EAD) plays an important role in arrhythmogenesis. Many experimental studies have reported that Ca(2+)/calmodulin-dependent protein kinase II (CaMKII) and β-adrenergic signaling pathway are two important regulators. In this study, we developed a modified computational model...

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Detalles Bibliográficos
Autores principales: Dai, Ling, Zang, Yunliang, Zheng, Dingchang, Xia, Ling, Gong, Yinglan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5178856/
https://www.ncbi.nlm.nih.gov/pubmed/28053652
http://dx.doi.org/10.1155/2016/4576313

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