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Pathophysiological Consequences of a Break in S1P1-Dependent Homeostasis of Vascular Permeability Revealed by S1P1 Competitive Antagonism
RATIONAL: Homeostasis of vascular barriers depends upon sphingosine 1-phosphate (S1P) signaling via the S1P1 receptor. Accordingly, S1P1 competitive antagonism is known to reduce vascular barrier integrity with still unclear pathophysiological consequences. This was explored in the present study usi...
Autores principales: | Bigaud, Marc, Dincer, Zuhal, Bollbuck, Birgit, Dawson, Janet, Beckmann, Nicolau, Beerli, Christian, Fishli-Cavelti, Gina, Nahler, Michaela, Angst, Daniela, Janser, Philipp, Otto, Heike, Rosner, Elisabeth, Hersperger, Rene, Bruns, Christian, Quancard, Jean |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5179015/ https://www.ncbi.nlm.nih.gov/pubmed/28005953 http://dx.doi.org/10.1371/journal.pone.0168252 |
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