An Intranasal Proteosome-Adjuvanted Trivalent Influenza Vaccine Is Safe, Immunogenic & Efficacious in the Human Viral Influenza Challenge Model. Serum IgG & Mucosal IgA Are Important Correlates of Protection against Illness Associated with Infection

INTRODUCTION: A Proteosome-adjuvanted trivalent inactivated influenza vaccine (P-TIV) administered intra-nasally was shown to be safe, well tolerated and immunogenic in both systemic and mucosal compartments, and effective at preventing illness associated with evidence of influenza infection. METHOD...

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Detalles Bibliográficos
Autores principales: Lambkin-Williams, Rob, Gelder, Colin, Broughton, Richard, Mallett, Corey P., Gilbert, Anthony S., Mann, Alex, He, David, Oxford, John S., Burt, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5179046/
https://www.ncbi.nlm.nih.gov/pubmed/28005959
http://dx.doi.org/10.1371/journal.pone.0163089

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