CGG Repeats in the 5’UTR of FMR1 RNA Regulate Translation of Other RNAs Localized in the Same RNA Granules

CGG repeats in the 5’UTR of Fragile X Mental Retardation 1 (FMR1) RNA mediate RNA localization and translation in granules. Large expansions of CGG repeats (> 200 repeats) in FMR1, referred to as full mutations, are associated with fragile X syndrome (FXS). Smaller expansions (55–200 repeats), re...

Descripción completa

Detalles Bibliográficos
Autores principales: Rovozzo, René, Korza, George, Baker, Mei W., Li, Meng, Bhattacharyya, Anita, Barbarese, Elisa, Carson, John H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5179066/
https://www.ncbi.nlm.nih.gov/pubmed/28005950
http://dx.doi.org/10.1371/journal.pone.0168204

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5179066/
https://www.ncbi.nlm.nih.gov/pubmed/28005950
http://dx.doi.org/10.1371/journal.pone.0168204

Ejemplares similares