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CGG Repeats in the 5’UTR of FMR1 RNA Regulate Translation of Other RNAs Localized in the Same RNA Granules
CGG repeats in the 5’UTR of Fragile X Mental Retardation 1 (FMR1) RNA mediate RNA localization and translation in granules. Large expansions of CGG repeats (> 200 repeats) in FMR1, referred to as full mutations, are associated with fragile X syndrome (FXS). Smaller expansions (55–200 repeats), re...
Autores principales: | Rovozzo, René, Korza, George, Baker, Mei W., Li, Meng, Bhattacharyya, Anita, Barbarese, Elisa, Carson, John H. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5179066/ https://www.ncbi.nlm.nih.gov/pubmed/28005950 http://dx.doi.org/10.1371/journal.pone.0168204 |
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