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MTOR-Driven Metabolic Reprogramming Regulates Legionella pneumophila Intracellular Niche Homeostasis
Vacuolar bacterial pathogens are sheltered within unique membrane-bound organelles that expand over time to support bacterial replication. These compartments sequester bacterial molecules away from host cytosolic immunosurveillance pathways that induce antimicrobial responses. The mechanisms by whic...
Autores principales: | Abshire, Camille F., Dragoi, Ana-Maria, Roy, Craig R., Ivanov, Stanimir S. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5179073/ https://www.ncbi.nlm.nih.gov/pubmed/27942021 http://dx.doi.org/10.1371/journal.ppat.1006088 |
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