Downregulation of TGF-β Receptor-2 Expression and Signaling through Inhibition of Na/K-ATPase

Transforming growth factor-beta (TGF-β) is a multi-functional cytokine implicated in the control of cell growth and differentiation. TGF-β signals through a complex of TGF-β receptors 1 and 2 (TGFβR1 and TGFβR2) that phosphorylate and activate Smad2/3 transcription factors driving transcription of t...

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Detalles Bibliográficos
Autores principales: La, Jennifer, Reed, Eleanor, Chan, Lan, Smolyaninova, Larisa V., Akomova, Olga A., Mutlu, Gökhan M., Orlov, Sergei N., Dulin, Nickolai O.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5179089/
https://www.ncbi.nlm.nih.gov/pubmed/28006004
http://dx.doi.org/10.1371/journal.pone.0168363

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5179089/
https://www.ncbi.nlm.nih.gov/pubmed/28006004
http://dx.doi.org/10.1371/journal.pone.0168363

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