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Downregulation of TGF-β Receptor-2 Expression and Signaling through Inhibition of Na/K-ATPase
Transforming growth factor-beta (TGF-β) is a multi-functional cytokine implicated in the control of cell growth and differentiation. TGF-β signals through a complex of TGF-β receptors 1 and 2 (TGFβR1 and TGFβR2) that phosphorylate and activate Smad2/3 transcription factors driving transcription of t...
Autores principales: | La, Jennifer, Reed, Eleanor, Chan, Lan, Smolyaninova, Larisa V., Akomova, Olga A., Mutlu, Gökhan M., Orlov, Sergei N., Dulin, Nickolai O. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5179089/ https://www.ncbi.nlm.nih.gov/pubmed/28006004 http://dx.doi.org/10.1371/journal.pone.0168363 |
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