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Mode of Delivery and Pregnancy Outcome in Women with Congenital Heart Disease

BACKGROUND: Advances in cardiac surgery and congenital cardiology have led to an increasing number of women with congenital heart disease (CHD) reaching childbearing age. In general, cardiologists recommend vaginal delivery for women with CHD to avoid complications from Caesarean section as many wom...

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Autores principales: Hrycyk, Joris, Kaemmerer, Harald, Nagdyman, Nicole, Hamann, Moritz, Schneider, KTM, Kuschel, Bettina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5179127/
https://www.ncbi.nlm.nih.gov/pubmed/28006009
http://dx.doi.org/10.1371/journal.pone.0167820
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author Hrycyk, Joris
Kaemmerer, Harald
Nagdyman, Nicole
Hamann, Moritz
Schneider, KTM
Kuschel, Bettina
author_facet Hrycyk, Joris
Kaemmerer, Harald
Nagdyman, Nicole
Hamann, Moritz
Schneider, KTM
Kuschel, Bettina
author_sort Hrycyk, Joris
collection PubMed
description BACKGROUND: Advances in cardiac surgery and congenital cardiology have led to an increasing number of women with congenital heart disease (CHD) reaching childbearing age. In general, cardiologists recommend vaginal delivery for women with CHD to avoid complications from Caesarean section as many women with CHD tolerate vaginal delivery well. METHODS AND RESULTS: This is a single-center study comparing mode of delivery, pregnancy outcome, indications for Caesarean section and induction of labor between women with and without CHD. A historical cohort study was conducted including 116 patients with CHD. An individual threefold matching with 348 women without CHD was carried out. Caesarean section was performed in 46.6% of pregnancies with CHD (33.6% without CHD, P = 0.012). Primary Caesarean section increases with severity of CHD (P = 0.036), 33.3% of women with CHD had primary planned Caesarean section due to cardiac reasons. Induction of labor was performed in 45.7% of attempted vaginal deliveries in women with CHD (27.9% without CHD, P = 0.001). Lower mean birth weight (P = 0.004) and Small for Gestational Age (SGA) (P < 0.001) were more common in women with CHD. One CHD patient suffered from postpartum hemorrhage. CONCLUSIONS: Concerns about maternal deterioration resulting in higher rates of induction of labor seem unjustified in most cases. Along with a possible reduction of Caesarean section on maternal request, a reduction of planned vaginal delivery may be expedient in reducing the rate of Caesarean section in women with CHD.
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spelling pubmed-51791272017-01-04 Mode of Delivery and Pregnancy Outcome in Women with Congenital Heart Disease Hrycyk, Joris Kaemmerer, Harald Nagdyman, Nicole Hamann, Moritz Schneider, KTM Kuschel, Bettina PLoS One Research Article BACKGROUND: Advances in cardiac surgery and congenital cardiology have led to an increasing number of women with congenital heart disease (CHD) reaching childbearing age. In general, cardiologists recommend vaginal delivery for women with CHD to avoid complications from Caesarean section as many women with CHD tolerate vaginal delivery well. METHODS AND RESULTS: This is a single-center study comparing mode of delivery, pregnancy outcome, indications for Caesarean section and induction of labor between women with and without CHD. A historical cohort study was conducted including 116 patients with CHD. An individual threefold matching with 348 women without CHD was carried out. Caesarean section was performed in 46.6% of pregnancies with CHD (33.6% without CHD, P = 0.012). Primary Caesarean section increases with severity of CHD (P = 0.036), 33.3% of women with CHD had primary planned Caesarean section due to cardiac reasons. Induction of labor was performed in 45.7% of attempted vaginal deliveries in women with CHD (27.9% without CHD, P = 0.001). Lower mean birth weight (P = 0.004) and Small for Gestational Age (SGA) (P < 0.001) were more common in women with CHD. One CHD patient suffered from postpartum hemorrhage. CONCLUSIONS: Concerns about maternal deterioration resulting in higher rates of induction of labor seem unjustified in most cases. Along with a possible reduction of Caesarean section on maternal request, a reduction of planned vaginal delivery may be expedient in reducing the rate of Caesarean section in women with CHD. Public Library of Science 2016-12-22 /pmc/articles/PMC5179127/ /pubmed/28006009 http://dx.doi.org/10.1371/journal.pone.0167820 Text en © 2016 Hrycyk et al http://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/) , which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Research Article
Hrycyk, Joris
Kaemmerer, Harald
Nagdyman, Nicole
Hamann, Moritz
Schneider, KTM
Kuschel, Bettina
Mode of Delivery and Pregnancy Outcome in Women with Congenital Heart Disease
title Mode of Delivery and Pregnancy Outcome in Women with Congenital Heart Disease
title_full Mode of Delivery and Pregnancy Outcome in Women with Congenital Heart Disease
title_fullStr Mode of Delivery and Pregnancy Outcome in Women with Congenital Heart Disease
title_full_unstemmed Mode of Delivery and Pregnancy Outcome in Women with Congenital Heart Disease
title_short Mode of Delivery and Pregnancy Outcome in Women with Congenital Heart Disease
title_sort mode of delivery and pregnancy outcome in women with congenital heart disease
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5179127/
https://www.ncbi.nlm.nih.gov/pubmed/28006009
http://dx.doi.org/10.1371/journal.pone.0167820
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