Cargando…

Experimental reconstitution of chronic ER stress in the liver reveals feedback suppression of BiP mRNA expression

Endoplasmic reticulum (ER) stress is implicated in many chronic diseases, but very little is known about how the unfolded protein response (UPR) responds to persistent ER stress in vivo. Here, we experimentally reconstituted chronic ER stress in the mouse liver, using repeated injection of a low dos...

Descripción completa

Detalles Bibliográficos
Autores principales:	Gomez, Javier A, Rutkowski, D Thomas
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	eLife Sciences Publications, Ltd 2016
Materias:	Cell Biology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5179193/ https://www.ncbi.nlm.nih.gov/pubmed/27938665 http://dx.doi.org/10.7554/eLife.20390

Ejemplares similares

Ratiometric sensing of BiP-client versus BiP levels by the unfolded protein response determines its signaling amplitude
por: Bakunts, Anush, et al.
Publicado: (2017)

Inadequate BiP availability defines endoplasmic reticulum stress
por: Vitale, Milena, et al.
Publicado: (2019)

BiP chaperones ER entry
por: LeBrasseur, Nicole
Publicado: (2005)

Adaptation to constant light requires Fic-mediated AMPylation of BiP to protect against reversible photoreceptor degeneration
por: Moehlman, Andrew T, et al.
Publicado: (2018)

Unstructured regions in IRE1α specify BiP-mediated destabilisation of the luminal domain dimer and repression of the UPR
por: Amin-Wetzel, Niko, et al.
Publicado: (2019)

GPNMB Induces BiP Expression by Enhancing Splicing of BiP Pre-mRNA during the Endoplasmic Reticulum Stress Response
por: Noda, Yasuhiro, et al.
Publicado: (2017)

ER chaperone GRP78/BiP translocates to the nucleus under stress and acts as a transcriptional regulator
por: Liu, Ze, et al.
Publicado: (2023)

Generation of human ER chaperone BiP in yeast Saccharomyces cerevisiae
por: Čiplys, Evaldas, et al.
Publicado: (2014)

Self-Association of Purified Reconstituted ER Luminal Spacer Climp63
por: Zhao, Jinghua, et al.
Publicado: (2020)

BiP Heterozigosity Aggravates Pathological Deterioration in Experimental Amyotrophic Lateral Sclerosis
por: Gómez-Almería, Marta, et al.
Publicado: (2021)

Live imaging of the co-translational recruitment of XBP1 mRNA to the ER and its processing by diffuse, non-polarized IRE1α
por: Gómez-Puerta, Silvia, et al.
Publicado: (2022)

The endoplasmic reticulum chaperone BiP is a closure-accelerating cochaperone of Grp94
por: Huang, Bin, et al.
Publicado: (2022)

A novel pathogenic role of the ER chaperone GRP78/BiP in rheumatoid arthritis
por: Yoo, Seung-Ah, et al.
Publicado: (2012)

A Sec63p-BiP complex from yeast is required for protein translocation in a reconstituted proteoliposome
Publicado: (1993)

In vitro reconstitution of branching microtubule nucleation
por: Tariq, Ammarah, et al.
Publicado: (2020)

Calcium depletion challenges endoplasmic reticulum proteostasis by destabilising BiP-substrate complexes
por: Preissler, Steffen, et al.
Publicado: (2020)

UPR proteins IRE1 and PERK switch BiP from chaperone to ER stress sensor
por: Kopp, Megan C, et al.
Publicado: (2019)

An oligomeric state‐dependent switch in the ER enzyme FICD regulates AMPylation and deAMPylation of BiP
por: Perera, Luke A, et al.
Publicado: (2019)

It's a chaperone … it's a gatekeeper … it's BiP
por: Dove, Alan W.
Publicado: (2002)

A big BiP on the radar screen
por: Powell, Kendall
Publicado: (2005)

BiP prevents rod opsin aggregation
por: Athanasiou, Dimitra, et al.
Publicado: (2012)

BiP Negatively Affects Ricin Transport
por: Gregers, Tone F., et al.
Publicado: (2013)

Reconstitution of protein translocation from solubilized yeast membranes reveals topologically distinct roles for BiP and cytosolic Hsc70
Publicado: (1993)

AMPylation targets the rate-limiting step of BiP’s ATPase cycle for its functional inactivation
por: Preissler, Steffen, et al.
Publicado: (2017)

Positive Feedback Stimulation of Ccnb1 and Mos mRNA Translation by MAPK Cascade During Mouse Oocyte Maturation
por: Cao, Lan-Rui, et al.
Publicado: (2020)

Regulation of mRNA translation during mitosis
por: Tanenbaum, Marvin E, et al.
Publicado: (2015)

The Lumenal Domain of Sec63p Stimulates the ATPase Activity of BiP and Mediates BiP Recruitment to the Translocon in Saccharomyces cerevisiae
por: Corsi, Ann K., et al.
Publicado: (1997)

Detection of autoantibodies to citrullinated BiP in rheumatoid arthritis patients and pro-inflammatory role of citrullinated BiP in collagen-induced arthritis
por: Shoda, Hirofumi, et al.
Publicado: (2011)

Genome-wide identification and characterization of Solanum tuberosum BiP genes reveal the role of the promoter architecture in BiP gene diversity
por: Herath, Venura, et al.
Publicado: (2020)

A new role for BiP: closing the aqueous translocon pore during protein integration into the ER membrane
por: Haigh, Nora G., et al.
Publicado: (2002)

Long-term sensitization training in Aplysia leads to an increase in the expression of BiP, the major protein chaperon of the ER
Publicado: (1992)

Interaction between BiP and Sec63p is required for the completion of protein translocation into the ER of Saccharomyces cerevisiae
Publicado: (1995)

BiP Binding to the ER-Stress Sensor Ire1 Tunes the Homeostatic Behavior of the Unfolded Protein Response
por: Pincus, David, et al.
Publicado: (2010)

Cancer cells adapt FAM134B/BiP mediated ER-phagy to survive hypoxic stress
por: Chipurupalli, Sandhya, et al.
Publicado: (2022)

Regulated Ire1-dependent mRNA decay requires no-go mRNA degradation to maintain endoplasmic reticulum homeostasis in S. pombe
por: Guydosh, Nicholas R, et al.
Publicado: (2017)

In vitro FRET analysis of IRE1 and BiP association and dissociation upon endoplasmic reticulum stress
por: Kopp, Megan C, et al.
Publicado: (2018)

BHLHE40, a third transcription factor required for insulin induction of SREBP-1c mRNA in rodent liver
por: Tian, Jing, et al.
Publicado: (2018)

Allosteric fine-tuning of the conformational equilibrium poises the chaperone BiP for post-translational regulation
por: Wieteska, Lukasz, et al.
Publicado: (2017)

RNA-directed activation of cytoplasmic dynein-1 in reconstituted transport RNPs
por: McClintock, Mark A, et al.
Publicado: (2018)

The In Vivo Association of BiP with Newly Synthesized Proteins Is Dependent on the Rate and Stability of Folding and Not Simply on the Presence of Sequences That Can Bind to BiP
por: Hellman, Rachel, et al.
Publicado: (1999)

Cannot write session to /tmp/vufind_sessions/sess_96babhjaob7l649n44guhjsudt