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Experimental reconstitution of chronic ER stress in the liver reveals feedback suppression of BiP mRNA expression

Endoplasmic reticulum (ER) stress is implicated in many chronic diseases, but very little is known about how the unfolded protein response (UPR) responds to persistent ER stress in vivo. Here, we experimentally reconstituted chronic ER stress in the mouse liver, using repeated injection of a low dos...

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Detalles Bibliográficos
Autores principales:	Gomez, Javier A, Rutkowski, D Thomas
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	eLife Sciences Publications, Ltd 2016
Materias:	Cell Biology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5179193/ https://www.ncbi.nlm.nih.gov/pubmed/27938665 http://dx.doi.org/10.7554/eLife.20390

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