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A quality by design approach on polymeric nanocarrier delivery of gefitinib: formulation, in vitro, and in vivo characterization

Gefitinib is an anticancer agent which acts by inhibiting epidermal growth factor receptor tyrosine kinase receptors. The aim of the present study was to prepare gefitinib nanosuspension. Gefitinib was encapsulated in Eudragit(®) RL100 and then dispersed in stabilizer solution, polyvinyl alcohol, an...

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Detalles Bibliográficos
Autores principales: Kola Srinivas, Navya Sree, Verma, Ruchi, Pai Kulyadi, Girish, Kumar, Lalit
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5179202/
https://www.ncbi.nlm.nih.gov/pubmed/28031710
http://dx.doi.org/10.2147/IJN.S122729