GSK249320, A Monoclonal Antibody Against the Axon Outgrowth Inhibition Molecule Myelin-Associated Glycoprotein, Improves Outcome of Rodents with Experimental Stroke

Myelin-associated glycoprotein (MAG) is an inhibitor of axon growth. MAG levels increase after stroke. GSK249320 is a monoclonal antibody that neutralizes MAG-mediated inhibition and so may promote axon outgrowth and improve post-stroke outcomes. The current study tested the hypothesis that GSK24932...

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Detalles Bibliográficos
Autores principales: Cash, Diana, Easton, Alanna C., Mesquita, Michel, Beech, John, Williams, Steve, Lloyd, Andrew, Irving, Elaine, Cramer, Steven C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5179224/
https://www.ncbi.nlm.nih.gov/pubmed/28018988

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