Glycogen Synthase Kinase-3 regulates IGFBP-1 gene transcription through the Thymine-rich Insulin Response Element

BACKGROUND: Hepatic expression of several gene products involved in glucose metabolism, including phosphoenolpyruvate carboxykinase (PEPCK), glucose-6-phosphatase (G6Pase) and insulin-like growth factor binding protein-1 (IGFBP-1), is rapidly and completely inhibited by insulin. This inhibition is m...

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Detalles Bibliográficos
Autores principales: Finlay, David, Patel, Satish, Dickson, Lorna M, Shpiro, Natalia, Marquez, Rodolfo, Rhodes, Chris J, Sutherland, Calum
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2004
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC517930/
https://www.ncbi.nlm.nih.gov/pubmed/15350195
http://dx.doi.org/10.1186/1471-2199-5-15

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