Fluconazole and Echinocandin Resistance of Candida glabrata Correlates Better with Antifungal Drug Exposure Rather than with MSH2 Mutator Genotype in a French Cohort of Patients Harboring Low Rates of Resistance

Candida glabrata is a major pathogenic yeast in humans that is known to rapidly acquire resistance to triazole and echinocandin antifungal drugs. A mutator genotype (MSH2 polymorphism) inducing a mismatch repair defect has been recently proposed to be responsible for resistance acquisition in C. gla...

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Detalles Bibliográficos
Autores principales: Dellière, Sarah, Healey, Kelley, Gits-Muselli, Maud, Carrara, Bastien, Barbaro, Alessandro, Guigue, Nicolas, Lecefel, Christophe, Touratier, Sophie, Desnos-Ollivier, Marie, Perlin, David S., Bretagne, Stéphane, Alanio, Alexandre
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2016
Materias:
Microbiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5179511/
https://www.ncbi.nlm.nih.gov/pubmed/28066361
http://dx.doi.org/10.3389/fmicb.2016.02038

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