Cargando…

Commentary: Parkinson disease-linked GBA mutation effects reversed by molecular chaperones in human cell and fly models

Detalles Bibliográficos
Autores principales:	Fernandes, Hugo J. R., Ryan, Brent J., Wade-Martins, Richard
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2016
Materias:	Neuroscience
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5179548/ https://www.ncbi.nlm.nih.gov/pubmed/28066164 http://dx.doi.org/10.3389/fnins.2016.00578

Ejemplares similares

Parkinson disease-linked GBA mutation effects reversed by molecular chaperones in human cell and fly models
por: Sanchez-Martinez, Alvaro, et al.
Publicado: (2016)

Glucocerebrosidase Mutations and Synucleinopathies. Potential Role of Sterylglucosides and Relevance of Studying Both GBA1 and GBA2 Genes
por: Franco, Rafael, et al.
Publicado: (2018)

Small Molecule Chaperones for the Treatment of Gaucher Disease and GBA1-Associated Parkinson Disease
por: Han, Tae-Un, et al.
Publicado: (2020)

No evidence for substrate accumulation in Parkinson brains with GBA mutations
por: Gegg, Matthew E., et al.
Publicado: (2015)

Association of GBA genotype with motor and cognitive decline in Chinese Parkinson’s disease patients
por: Ren, Jingru, et al.
Publicado: (2023)

Commentary: Metformin reverses TRAP1 mutation-associated alterations in mitochondrial function in Parkinson's disease
por: Rai, Sachchida N., et al.
Publicado: (2018)

Gene Therapy for Parkinson’s Disease Associated with GBA1 Mutations
por: Abeliovich, Asa, et al.
Publicado: (2021)

The Consequences of GBA Deficiency in the Autophagy–Lysosome System in Parkinson’s Disease Associated with GBA
por: Pradas, Eddie, et al.
Publicado: (2023)

α-Synuclein accumulation and GBA deficiency due to L444P GBA mutation contributes to MPTP-induced parkinsonism
por: Yun, Seung Pil, et al.
Publicado: (2018)

Comparative Transcriptome Analysis in Monocyte-Derived Macrophages of Asymptomatic GBA Mutation Carriers and Patients with GBA-Associated Parkinson’s Disease
por: Usenko, Tatiana, et al.
Publicado: (2021)

Integrated Genetic Analysis of Racial Differences of Common GBA Variants in Parkinson's Disease: A Meta-Analysis
por: Zhang, Yuan, et al.
Publicado: (2018)

Lack of Association Between GBA Mutations and Motor Complications in European and American Parkinson’s Disease Cohorts
por: Maple-Grødem, Jodi, et al.
Publicado: (2021)

Plasma Glucosylsphingosine in GBA1 Mutation Carriers with and without Parkinson's Disease
por: Surface, Matthew, et al.
Publicado: (2021)

Parkinson’s Disease Associated with GBA Gene Mutations: Molecular Aspects and Potential Treatment Approaches
por: Senkevich, K. A., et al.
Publicado: (2021)

ER Stress and Autophagic Perturbations Lead to Elevated Extracellular α-Synuclein in GBA-N370S Parkinson's iPSC-Derived Dopamine Neurons
por: Fernandes, Hugo J.R., et al.
Publicado: (2016)

Visual short-term memory deficits associated with GBA mutation and Parkinson’s disease
por: Zokaei, Nahid, et al.
Publicado: (2014)

Dual-Task Performance in GBA Parkinson's Disease
por: Srulijes, Karin, et al.
Publicado: (2017)

GBA Variants and Parkinson Disease: Mechanisms and Treatments
por: Smith, Laura, et al.
Publicado: (2022)

The Enigmatic Role of GBA2 in Controlling Locomotor Function
por: Woeste, Marina A., et al.
Publicado: (2017)

Deregulation of mTORC1-TFEB axis in human iPSC model of GBA1-associated Parkinson’s disease
por: Mubariz, Fahad, et al.
Publicado: (2023)

Brain Microglial Activation Increased in Glucocerebrosidase (GBA) Mutation Carriers without Parkinson's disease
por: Mullin, Stephen, et al.
Publicado: (2020)

Cross-talks among GBA mutations, glucocerebrosidase, and α-synuclein in GBA-associated Parkinson’s disease and their targeted therapeutic approaches: a comprehensive review
por: Behl, Tapan, et al.
Publicado: (2021)

Longitudinal evaluation of olfactory function in individuals with Gaucher disease and GBA1 mutation carriers with and without Parkinson's disease
por: Lopez, Grisel J., et al.
Publicado: (2022)

Levodopa-Induced Ocular Dyskinesia in an Early-Onset Parkinson Disease Patient With GBA Mutation
por: He, Jia-Ming, et al.
Publicado: (2021)

Should we offer deep brain stimulation to Parkinson’s disease patients with GBA mutations?
por: Artusi, Carlo Alberto, et al.
Publicado: (2023)

SWATH Mass Spectrometry-Based CSF Proteome Profile of GBA-Linked Parkinson’s Disease Patients
por: Zafar, Saima, et al.
Publicado: (2022)

Sex-Specific Microglial Responses to Glucocerebrosidase Inhibition: Relevance to GBA1-Linked Parkinson’s Disease
por: Brunialti, Electra, et al.
Publicado: (2023)

Experience in Genetic Counseling for GBA1 Variants in Parkinson's Disease
por: den Heijer, Jonas M., et al.
Publicado: (2020)

Unraveling Autonomic Dysfunction in GBA‐Related Parkinson's Disease
por: Devigili, Grazia, et al.
Publicado: (2023)

Features of GBA-associated Parkinson’s disease at presentation in the UK Tracking Parkinson’s study
por: Malek, Naveed, et al.
Publicado: (2018)

Elevation of gangliosides in four brain regions from Parkinson’s disease patients with a GBA mutation
por: Blumenreich, Shani, et al.
Publicado: (2022)

Mutational spectrum and clinical features of GBA1 variants in a Chinese cohort with Parkinson’s disease
por: Zhou, Yangjie, et al.
Publicado: (2023)

Endoplasmic reticulum and lysosomal Ca(2+) stores are remodelled in GBA1-linked Parkinson disease patient fibroblasts
por: Kilpatrick, Bethan S., et al.
Publicado: (2016)

A molecular analysis of the GBA gene in Caucasian South Africans with Parkinson's disease
por: Barkhuizen, Melinda, et al.
Publicado: (2017)

Role of Chaperone-Mediated Autophagy Dysfunctions in the Pathogenesis of Parkinson’s Disease
por: Sala, Gessica, et al.
Publicado: (2016)

GBA1 in Parkinson’s disease: variant detection and pathogenicity scoring matters
por: Gabbert, Carolin, et al.
Publicado: (2023)

Effect of GBA Mutations on Phenotype of Parkinson's Disease: A Study on Chinese Population and a Meta-Analysis
por: Zhang, Yuan, et al.
Publicado: (2015)

Sphingolipid changes in Parkinson L444P GBA mutation fibroblasts promote α-synuclein aggregation
por: Galvagnion, Céline, et al.
Publicado: (2022)

GBA Variants Influence Motor and Non-Motor Features of Parkinson’s Disease
por: Jesús, Silvia, et al.
Publicado: (2016)

The Association between E326K of GBA and the Risk of Parkinson's Disease
por: Huang, Yongpan, et al.
Publicado: (2018)

Cannot write session to /tmp/vufind_sessions/sess_e7qdn9gg568be8sgbvpmsg1rf9