Loss of MeCP2 in the rat models regression, impaired sociability and transcriptional deficits of Rett syndrome

Mouse models of the transcriptional modulator Methyl-CpG-Binding Protein 2 (MeCP2) have advanced our understanding of Rett syndrome (RTT). RTT is a ‘prototypical’ neurodevelopmental disorder with many clinical features overlapping with other intellectual and developmental disabilities (IDD). Therape...

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Detalles Bibliográficos
Autores principales: Veeraragavan, Surabi, Wan, Ying-Wooi, Connolly, Daniel R., Hamilton, Shannon M., Ward, Christopher S., Soriano, Sirena, Pitcher, Meagan R., McGraw, Christopher M., Huang, Sharon G., Green, Jennie R., Yuva, Lisa A., Liang, Agnes J., Neul, Jeffrey L., Yasui, Dag H., LaSalle, Janine M., Liu, Zhandong, Paylor, Richard, Samaco, Rodney C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2016
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5179927/
https://www.ncbi.nlm.nih.gov/pubmed/27365498
http://dx.doi.org/10.1093/hmg/ddw178

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