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MeCP2 deficiency results in robust Rett-like behavioural and motor deficits in male and female rats

Since the identification of MECP2 as the causative gene in the majority of Rett Syndrome (RTT) cases, transgenic mouse models have played a critical role in our understanding of this disease. The use of additional mammalian RTT models offers the promise of further elucidating critical early mechanis...

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Detalles Bibliográficos
Autores principales: Patterson, Kelsey C., Hawkins, Virginia E., Arps, Kara M., Mulkey, Daniel K., Olsen, Michelle L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5179928/
https://www.ncbi.nlm.nih.gov/pubmed/27329765
http://dx.doi.org/10.1093/hmg/ddw179

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