Ectodysplasin signalling deficiency in mouse models of hypohidrotic ectodermal dysplasia leads to middle ear and nasal pathology

Hypohidrotic ectodermal dysplasia (HED) results from mutation of the EDA, EDAR or EDARADD genes and is characterized by reduced or absent eccrine sweat glands, hair follicles and teeth, and defective formation of salivary, mammary and craniofacial glands. Mouse models with HED also carry Eda, Edar o...

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Detalles Bibliográficos
Autores principales: Azar, Ali, Piccinelli, Chiara, Brown, Helen, Headon, Denis, Cheeseman, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2016
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5179950/
https://www.ncbi.nlm.nih.gov/pubmed/27378689
http://dx.doi.org/10.1093/hmg/ddw202

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