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Acetyl-11-Keto-β-Boswellic Acid Attenuates Prooxidant and Profibrotic Mechanisms Involving Transforming Growth Factor-β1, and Improves Vascular Remodeling in Spontaneously Hypertensive Rats
Vascular remodeling is an important complication of hypertension with oxidative stress-related profibrotic pathways involved. The transforming growth factor β1 (TGF-β1) has been shown to be a potential target of vasoprotection, and has multiple roles in vascular remodeling. Acetyl-11-Keto-β-Boswelli...
Autores principales: | Shang, Peijin, Liu, Wenxing, Liu, Tianlong, Zhang, Yikai, Mu, Fei, Zhu, Zhihui, Liang, Lingfei, Zhai, Xiaohu, Ding, Yi, Li, Yuwen, Wen, Aidong |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5180224/ https://www.ncbi.nlm.nih.gov/pubmed/28009003 http://dx.doi.org/10.1038/srep39809 |
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