The C-terminus of IGFBP-5 suppresses tumor growth by inhibiting angiogenesis

Insulin-like growth factor-binding protein 5 (IGFBP-5) plays a role in cell growth, differentiation, and apoptosis. In this study, we found that IGFBP5 was markedly downregulated in ovarian cancer tissue. We investigated the functional significance of IGFBP-5 as a tumor suppressor. To determine func...

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Detalles Bibliográficos
Autores principales: Hwang, Jae Ryoung, Cho, Young-Jae, Lee, Yoonna, Park, Youngmee, Han, Hee Dong, Ahn, Hyung Jun, Lee, Je-Ho, Lee, Jeong-Won
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5180245/
https://www.ncbi.nlm.nih.gov/pubmed/28008951
http://dx.doi.org/10.1038/srep39334

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5180245/
https://www.ncbi.nlm.nih.gov/pubmed/28008951
http://dx.doi.org/10.1038/srep39334

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