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A camel-derived MERS-CoV with a variant spike protein cleavage site and distinct fusion activation properties

Middle East respiratory syndrome coronavirus (MERS-CoV) continues to circulate in both humans and camels, and the origin and evolution of the virus remain unclear. Here we characterize the spike protein of a camel-derived MERS-CoV (NRCE-HKU205) identified in 2013, early in the MERS outbreak. NRCE-HK...

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Detalles Bibliográficos
Autores principales: Millet, Jean Kaoru, Goldstein, Monty E, Labitt, Rachael N, Hsu, Hung-Lun, Daniel, Susan, Whittaker, Gary R
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5180369/
https://www.ncbi.nlm.nih.gov/pubmed/27999426
http://dx.doi.org/10.1038/emi.2016.125

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