Cargando…
BioPartsDB: a synthetic biology workflow web-application for education and research
Summary: Synthetic biology has become a widely used technology, and expanding applications in research, education and industry require progress tracking for team-based DNA synthesis projects. Although some vendors are beginning to supply multi-kilobase sequence-verified constructs, synthesis workflo...
Autores principales: | , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2016
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5181553/ https://www.ncbi.nlm.nih.gov/pubmed/27412090 http://dx.doi.org/10.1093/bioinformatics/btw394 |
_version_ | 1782485730046509056 |
---|---|
author | Stracquadanio, Giovanni Yang, Kun Boeke, Jef D. Bader, Joel S. |
author_facet | Stracquadanio, Giovanni Yang, Kun Boeke, Jef D. Bader, Joel S. |
author_sort | Stracquadanio, Giovanni |
collection | PubMed |
description | Summary: Synthetic biology has become a widely used technology, and expanding applications in research, education and industry require progress tracking for team-based DNA synthesis projects. Although some vendors are beginning to supply multi-kilobase sequence-verified constructs, synthesis workflows starting with short oligos remain important for cost savings and pedagogical benefit. We developed BioPartsDB as an open source, extendable workflow management system for synthetic biology projects with entry points for oligos and larger DNA constructs and ending with sequence-verified clones. Availability and Implementation: BioPartsDB is released under the MIT license and available for download at https://github.com/baderzone/biopartsdb. Additional documentation and video tutorials are available at https://github.com/baderzone/biopartsdb/wiki. An Amazon Web Services image is available from the AWS Market Place (ami-a01d07c8). Contact: joel.bader@jhu.edu |
format | Online Article Text |
id | pubmed-5181553 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2016 |
publisher | Oxford University Press |
record_format | MEDLINE/PubMed |
spelling | pubmed-51815532016-12-27 BioPartsDB: a synthetic biology workflow web-application for education and research Stracquadanio, Giovanni Yang, Kun Boeke, Jef D. Bader, Joel S. Bioinformatics Applications Notes Summary: Synthetic biology has become a widely used technology, and expanding applications in research, education and industry require progress tracking for team-based DNA synthesis projects. Although some vendors are beginning to supply multi-kilobase sequence-verified constructs, synthesis workflows starting with short oligos remain important for cost savings and pedagogical benefit. We developed BioPartsDB as an open source, extendable workflow management system for synthetic biology projects with entry points for oligos and larger DNA constructs and ending with sequence-verified clones. Availability and Implementation: BioPartsDB is released under the MIT license and available for download at https://github.com/baderzone/biopartsdb. Additional documentation and video tutorials are available at https://github.com/baderzone/biopartsdb/wiki. An Amazon Web Services image is available from the AWS Market Place (ami-a01d07c8). Contact: joel.bader@jhu.edu Oxford University Press 2016-11-15 2016-07-13 /pmc/articles/PMC5181553/ /pubmed/27412090 http://dx.doi.org/10.1093/bioinformatics/btw394 Text en © The Author 2016. Published by Oxford University Press. http://creativecommons.org/licenses/by-nc/4.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0/), which permits non-commercial re-use, distribution, and reproduction in any medium, provided the original work is properly cited. For commercial re-use, please contact journals.permissions@oup.com |
spellingShingle | Applications Notes Stracquadanio, Giovanni Yang, Kun Boeke, Jef D. Bader, Joel S. BioPartsDB: a synthetic biology workflow web-application for education and research |
title | BioPartsDB: a synthetic biology workflow web-application for education and research |
title_full | BioPartsDB: a synthetic biology workflow web-application for education and research |
title_fullStr | BioPartsDB: a synthetic biology workflow web-application for education and research |
title_full_unstemmed | BioPartsDB: a synthetic biology workflow web-application for education and research |
title_short | BioPartsDB: a synthetic biology workflow web-application for education and research |
title_sort | biopartsdb: a synthetic biology workflow web-application for education and research |
topic | Applications Notes |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5181553/ https://www.ncbi.nlm.nih.gov/pubmed/27412090 http://dx.doi.org/10.1093/bioinformatics/btw394 |
work_keys_str_mv | AT stracquadaniogiovanni biopartsdbasyntheticbiologyworkflowwebapplicationforeducationandresearch AT yangkun biopartsdbasyntheticbiologyworkflowwebapplicationforeducationandresearch AT boekejefd biopartsdbasyntheticbiologyworkflowwebapplicationforeducationandresearch AT baderjoels biopartsdbasyntheticbiologyworkflowwebapplicationforeducationandresearch |