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BioPartsDB: a synthetic biology workflow web-application for education and research

Summary: Synthetic biology has become a widely used technology, and expanding applications in research, education and industry require progress tracking for team-based DNA synthesis projects. Although some vendors are beginning to supply multi-kilobase sequence-verified constructs, synthesis workflo...

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Detalles Bibliográficos
Autores principales: Stracquadanio, Giovanni, Yang, Kun, Boeke, Jef D., Bader, Joel S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5181553/
https://www.ncbi.nlm.nih.gov/pubmed/27412090
http://dx.doi.org/10.1093/bioinformatics/btw394
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author Stracquadanio, Giovanni
Yang, Kun
Boeke, Jef D.
Bader, Joel S.
author_facet Stracquadanio, Giovanni
Yang, Kun
Boeke, Jef D.
Bader, Joel S.
author_sort Stracquadanio, Giovanni
collection PubMed
description Summary: Synthetic biology has become a widely used technology, and expanding applications in research, education and industry require progress tracking for team-based DNA synthesis projects. Although some vendors are beginning to supply multi-kilobase sequence-verified constructs, synthesis workflows starting with short oligos remain important for cost savings and pedagogical benefit. We developed BioPartsDB as an open source, extendable workflow management system for synthetic biology projects with entry points for oligos and larger DNA constructs and ending with sequence-verified clones. Availability and Implementation: BioPartsDB is released under the MIT license and available for download at https://github.com/baderzone/biopartsdb. Additional documentation and video tutorials are available at https://github.com/baderzone/biopartsdb/wiki. An Amazon Web Services image is available from the AWS Market Place (ami-a01d07c8). Contact: joel.bader@jhu.edu
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spelling pubmed-51815532016-12-27 BioPartsDB: a synthetic biology workflow web-application for education and research Stracquadanio, Giovanni Yang, Kun Boeke, Jef D. Bader, Joel S. Bioinformatics Applications Notes Summary: Synthetic biology has become a widely used technology, and expanding applications in research, education and industry require progress tracking for team-based DNA synthesis projects. Although some vendors are beginning to supply multi-kilobase sequence-verified constructs, synthesis workflows starting with short oligos remain important for cost savings and pedagogical benefit. We developed BioPartsDB as an open source, extendable workflow management system for synthetic biology projects with entry points for oligos and larger DNA constructs and ending with sequence-verified clones. Availability and Implementation: BioPartsDB is released under the MIT license and available for download at https://github.com/baderzone/biopartsdb. Additional documentation and video tutorials are available at https://github.com/baderzone/biopartsdb/wiki. An Amazon Web Services image is available from the AWS Market Place (ami-a01d07c8). Contact: joel.bader@jhu.edu Oxford University Press 2016-11-15 2016-07-13 /pmc/articles/PMC5181553/ /pubmed/27412090 http://dx.doi.org/10.1093/bioinformatics/btw394 Text en © The Author 2016. Published by Oxford University Press. http://creativecommons.org/licenses/by-nc/4.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0/), which permits non-commercial re-use, distribution, and reproduction in any medium, provided the original work is properly cited. For commercial re-use, please contact journals.permissions@oup.com
spellingShingle Applications Notes
Stracquadanio, Giovanni
Yang, Kun
Boeke, Jef D.
Bader, Joel S.
BioPartsDB: a synthetic biology workflow web-application for education and research
title BioPartsDB: a synthetic biology workflow web-application for education and research
title_full BioPartsDB: a synthetic biology workflow web-application for education and research
title_fullStr BioPartsDB: a synthetic biology workflow web-application for education and research
title_full_unstemmed BioPartsDB: a synthetic biology workflow web-application for education and research
title_short BioPartsDB: a synthetic biology workflow web-application for education and research
title_sort biopartsdb: a synthetic biology workflow web-application for education and research
topic Applications Notes
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5181553/
https://www.ncbi.nlm.nih.gov/pubmed/27412090
http://dx.doi.org/10.1093/bioinformatics/btw394
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