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The heritability and patterns of DNA methylation in normal human colorectum

DNA methylation (DNAm) has been linked to changes in chromatin structure, gene expression and disease. The DNAm level can be affected by genetic variation; although, how this differs by CpG dinucleotide density and genic location of the DNAm site is not well understood. Moreover, the effect of disea...

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Detalles Bibliográficos
Autores principales: Rowlatt, Amy, Hernández-Suárez, Gustavo, Sanabria-Salas, María Carolina, Serrano-López, Martha, Rawlik, Konrad, Hernandez-Illan, Eva, Alenda, Cristina, Castillejo, Adela, Soto, Jose Luis, Haley, Chris S., Tenesa, Albert
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5181623/
https://www.ncbi.nlm.nih.gov/pubmed/26936820
http://dx.doi.org/10.1093/hmg/ddw072