Restoration of SMN in Schwann cells reverses myelination defects and improves neuromuscular function in spinal muscular atrophy

Spinal muscular atrophy (SMA) is a neuromuscular disease caused by low levels of SMN protein, primarily affecting lower motor neurons. Recent evidence from SMA and related conditions suggests that glial cells can influence disease severity. Here, we investigated the role of glial cells in the periph...

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Detalles Bibliográficos
Autores principales: Hunter, Gillian, Powis, Rachael A., Jones, Ross A., Groen, Ewout J.N., Shorrock, Hannah K., Lane, Fiona M., Zheng, Yinan, Sherman, Diane L., Brophy, Peter J., Gillingwater, Thomas H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2016
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5181642/
https://www.ncbi.nlm.nih.gov/pubmed/27170316
http://dx.doi.org/10.1093/hmg/ddw141

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5181642/
https://www.ncbi.nlm.nih.gov/pubmed/27170316
http://dx.doi.org/10.1093/hmg/ddw141

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