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New Gold in Them Thar Hills: Testing a Novel Supply Route for Plant-Derived Galanthamine

Many secondary plant compounds are synthesized in response to stressed growing conditions. We tested the feasibility of exploiting this feature in a novel strategy for the commercial production of the plant alkaloid galanthamine. Experimental lines of Narcissus pseudonarcissus were established under...

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Detalles Bibliográficos
Autores principales: Fraser, Mariecia D., Davies, John R.T., Chang, Xianmin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: IOS Press 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5181655/
https://www.ncbi.nlm.nih.gov/pubmed/27834779
http://dx.doi.org/10.3233/JAD-160791
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author Fraser, Mariecia D.
Davies, John R.T.
Chang, Xianmin
author_facet Fraser, Mariecia D.
Davies, John R.T.
Chang, Xianmin
author_sort Fraser, Mariecia D.
collection PubMed
description Many secondary plant compounds are synthesized in response to stressed growing conditions. We tested the feasibility of exploiting this feature in a novel strategy for the commercial production of the plant alkaloid galanthamine. Experimental lines of Narcissus pseudonarcissus were established under marginal upland permanent pasture at four different sites. Over 80% of bulbs successfully established at each site. There was no effect of altitude or planting density on galanthamine concentrations within vegetative tissues, which were higher than anticipated. The results confirm that planting N. pseudonarcissus under grass competition in upland areas could offer a novel and sustainable source of plant-derived galanthamine.
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spelling pubmed-51816552016-12-27 New Gold in Them Thar Hills: Testing a Novel Supply Route for Plant-Derived Galanthamine Fraser, Mariecia D. Davies, John R.T. Chang, Xianmin J Alzheimers Dis Short Communication Many secondary plant compounds are synthesized in response to stressed growing conditions. We tested the feasibility of exploiting this feature in a novel strategy for the commercial production of the plant alkaloid galanthamine. Experimental lines of Narcissus pseudonarcissus were established under marginal upland permanent pasture at four different sites. Over 80% of bulbs successfully established at each site. There was no effect of altitude or planting density on galanthamine concentrations within vegetative tissues, which were higher than anticipated. The results confirm that planting N. pseudonarcissus under grass competition in upland areas could offer a novel and sustainable source of plant-derived galanthamine. IOS Press 2016-12-20 /pmc/articles/PMC5181655/ /pubmed/27834779 http://dx.doi.org/10.3233/JAD-160791 Text en IOS Press and the authors. All rights reserved https://creativecommons.org/licenses/by-nc/4.0/ This is an open access article distributed under the terms of the Creative Commons Attribution Non-Commercial (CC BY-NC 4.0) License (https://creativecommons.org/licenses/by-nc/4.0/) , which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Short Communication
Fraser, Mariecia D.
Davies, John R.T.
Chang, Xianmin
New Gold in Them Thar Hills: Testing a Novel Supply Route for Plant-Derived Galanthamine
title New Gold in Them Thar Hills: Testing a Novel Supply Route for Plant-Derived Galanthamine
title_full New Gold in Them Thar Hills: Testing a Novel Supply Route for Plant-Derived Galanthamine
title_fullStr New Gold in Them Thar Hills: Testing a Novel Supply Route for Plant-Derived Galanthamine
title_full_unstemmed New Gold in Them Thar Hills: Testing a Novel Supply Route for Plant-Derived Galanthamine
title_short New Gold in Them Thar Hills: Testing a Novel Supply Route for Plant-Derived Galanthamine
title_sort new gold in them thar hills: testing a novel supply route for plant-derived galanthamine
topic Short Communication
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5181655/
https://www.ncbi.nlm.nih.gov/pubmed/27834779
http://dx.doi.org/10.3233/JAD-160791
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