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Strain Prioritization and Genome Mining for Enediyne Natural Products

The enediyne family of natural products has had a profound impact on modern chemistry, biology, and medicine, and yet only 11 enediynes have been structurally characterized to date. Here we report a genome survey of 3,400 actinomycetes, identifying 81 strains that harbor genes encoding the enediyne...

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Detalles Bibliográficos
Autores principales:	Yan, Xiaohui, Ge, Huiming, Huang, Tingting, Hindra, Yang, Dong, Teng, Qihui, Crnovčić, Ivana, Li, Xiuling, Rudolf, Jeffrey D., Lohman, Jeremy R., Gansemans, Yannick, Zhu, Xiangcheng, Huang, Yong, Zhao, Li-Xing, Jiang, Yi, Van Nieuwerburgh, Filip, Rader, Christoph, Duan, Yanwen, Shen, Ben
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Microbiology 2016
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5181780/ https://www.ncbi.nlm.nih.gov/pubmed/27999165 http://dx.doi.org/10.1128/mBio.02104-16

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