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PLD1 regulates adipogenic differentiation through mTOR - IRS-1 phosphorylation at serine 636/639
Phospholipase D1 (PLD1) plays a known role in several differentiation processes, but its role in adipogenic differentiation remains unknown. In the present study, we identified PLD1 as a negative regulator of adipogenic differentiation. We showed that PLD activity was downregulated by both 3-Isobuty...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Nature Publishing Group
2016
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5181839/ https://www.ncbi.nlm.nih.gov/pubmed/27872488 http://dx.doi.org/10.1038/srep36968 |