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Structure of the germline genome of Tetrahymena thermophila and relationship to the massively rearranged somatic genome

The germline genome of the binucleated ciliate Tetrahymena thermophila undergoes programmed chromosome breakage and massive DNA elimination to generate the somatic genome. Here, we present a complete sequence assembly of the germline genome and analyze multiple features of its structure and its rela...

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Detalles Bibliográficos
Autores principales: Hamilton, Eileen P, Kapusta, Aurélie, Huvos, Piroska E, Bidwell, Shelby L, Zafar, Nikhat, Tang, Haibao, Hadjithomas, Michalis, Krishnakumar, Vivek, Badger, Jonathan H, Caler, Elisabet V, Russ, Carsten, Zeng, Qiandong, Fan, Lin, Levin, Joshua Z, Shea, Terrance, Young, Sarah K, Hegarty, Ryan, Daza, Riza, Gujja, Sharvari, Wortman, Jennifer R, Birren, Bruce W, Nusbaum, Chad, Thomas, Jainy, Carey, Clayton M, Pritham, Ellen J, Feschotte, Cédric, Noto, Tomoko, Mochizuki, Kazufumi, Papazyan, Romeo, Taverna, Sean D, Dear, Paul H, Cassidy-Hanley, Donna M, Xiong, Jie, Miao, Wei, Orias, Eduardo, Coyne, Robert S
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5182062/
https://www.ncbi.nlm.nih.gov/pubmed/27892853
http://dx.doi.org/10.7554/eLife.19090