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Expanding the Repertoire of Carbapenem-Hydrolyzing Metallo-ß-Lactamases by Functional Metagenomic Analysis of Soil Microbiota

Carbapenemases are bacterial enzymes that hydrolyze carbapenems, a group of last-resort β-lactam antibiotics used for treatment of severe bacterial infections. They belong to three β-lactamase classes based amino acid sequence (A, B, and D). The aim of this study was to elucidate occurrence, diversi...

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Detalles Bibliográficos
Autores principales: Gudeta, Dereje D., Bortolaia, Valeria, Pollini, Simona, Docquier, Jean-Denis, Rossolini, Gian M., Amos, Gregory C. A., Wellington, Elizabeth M. H., Guardabassi, Luca
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5184135/
https://www.ncbi.nlm.nih.gov/pubmed/28082950
http://dx.doi.org/10.3389/fmicb.2016.01985