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Proteinase-Activated Receptor 2 Is a Novel Regulator of TGF-β Signaling in Pancreatic Cancer

TGF-β has a dual role in tumorigenesis, acting as a tumor suppressor in normal cells and in the early stages of tumor development while promoting carcinogenesis and metastasis in advanced tumor stages. The final outcome of the TGF-β response is determined by cell-autonomous mechanisms and genetic al...

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Detalles Bibliográficos
Autores principales:	Witte, David, Zeeh, Franziska, Gädeken, Thomas, Gieseler, Frank, Rauch, Bernhard H., Settmacher, Utz, Kaufmann, Roland, Lehnert, Hendrik, Ungefroren, Hendrik
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2016
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5184784/ https://www.ncbi.nlm.nih.gov/pubmed/27916875 http://dx.doi.org/10.3390/jcm5120111

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