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Inhibition of Poly-ADP-Ribosylation Fails to Increase Axonal Regeneration or Improve Functional Recovery after Adult Mammalian CNS Injury

After traumatic damage of the brain or spinal cord, many surviving neurons are disconnected, and recovery of function is limited by poor axon regeneration. Recent data have suggested that poly ADP-ribosylation plays a role in limiting axonal regrowth such that inhibition of poly (ADP-ribose) polymer...

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Detalles Bibliográficos
Autores principales:	Wang, Xingxing, Sekine, Yuichi, Byrne, Alexandra B., Cafferty, William B.J., Hammarlund, Marc, Strittmatter, Stephen M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Society for Neuroscience 2016
Materias:	Negative Results
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5187389/ https://www.ncbi.nlm.nih.gov/pubmed/28032120 http://dx.doi.org/10.1523/ENEURO.0270-16.2016

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