A Novel Method for N-terminal Acetylation Prediction

The NetAcet method has been developed to make predictions of N-terminal acetylation sites, but more information of the data set could be utilized to improve the performance of the model. By employing a new way to extract patterns from sequences and using a sample balancing mechanism, we obtained a c...

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Detalles Bibliográficos
Autores principales: Liu, Ying, Lin, Yuanlie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2004
Materias:
Brief Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5187419/
https://www.ncbi.nlm.nih.gov/pubmed/15901254
http://dx.doi.org/10.1016/S1672-0229(04)02032-7
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author Liu, Ying
Lin, Yuanlie
author_facet Liu, Ying
Lin, Yuanlie
author_sort Liu, Ying
collection PubMed
description The NetAcet method has been developed to make predictions of N-terminal acetylation sites, but more information of the data set could be utilized to improve the performance of the model. By employing a new way to extract patterns from sequences and using a sample balancing mechanism, we obtained a correlation coefficient of 0.85, and a sensitivity of 93% on an independent mammalian data set. A web server utilizing this method has been constructed and is available at http://166.111.24.5/acetylation.html.
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spelling pubmed-51874192017-01-03 A Novel Method for N-terminal Acetylation Prediction Liu, Ying Lin, Yuanlie Genomics Proteomics Bioinformatics Brief Report The NetAcet method has been developed to make predictions of N-terminal acetylation sites, but more information of the data set could be utilized to improve the performance of the model. By employing a new way to extract patterns from sequences and using a sample balancing mechanism, we obtained a correlation coefficient of 0.85, and a sensitivity of 93% on an independent mammalian data set. A web server utilizing this method has been constructed and is available at http://166.111.24.5/acetylation.html. Elsevier 2004-11 2016-11-28 /pmc/articles/PMC5187419/ /pubmed/15901254 http://dx.doi.org/10.1016/S1672-0229(04)02032-7 Text en . http://creativecommons.org/licenses/by-nc-nd/4.0/ This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Brief Report
Liu, Ying
Lin, Yuanlie
A Novel Method for N-terminal Acetylation Prediction
title A Novel Method for N-terminal Acetylation Prediction
title_full A Novel Method for N-terminal Acetylation Prediction
title_fullStr A Novel Method for N-terminal Acetylation Prediction
title_full_unstemmed A Novel Method for N-terminal Acetylation Prediction
title_short A Novel Method for N-terminal Acetylation Prediction
title_sort novel method for n-terminal acetylation prediction
topic Brief Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5187419/
https://www.ncbi.nlm.nih.gov/pubmed/15901254
http://dx.doi.org/10.1016/S1672-0229(04)02032-7
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